Whatever is the technology that you use to register the active backends in the DNS, rather than doing name => ip address lookup per request, you can resolve all those names => ip address maps upon the service being brought up/taken down and push the resolved map as a set of backends into nginx config, thus removing the need to query DNS per request.
Whatever is the technology that you use to register the active backends in the DNS, rather than doing name => ip address lookup per request, you can resolve all those names => ip address maps upon the service being brought up/taken down and push the resolved map as a set of backends into nginx config, thus removing the need to query DNS per request.